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Are you struggling with obesity and overweight? Or, are you an adult with type 2 diabetes? If yes, you’ve possibly heard of both Ozempic and Wegovy already. Right?

Both Wegovy and Ozempic are super famous worldwide, especially as weight-loss drugs. In general, they are GLP-1s (stands for glucagon-like peptide-1 receptor agonists) & have the same active ingredient (semaglutide).

No doubt, for people who are looking for weight loss drug to accelerate weight management, reduce hypertension or high cholesterol, or manage their type 2 diabetes, no other medications could serve a purpose like these two. And we can’t deny the perks they have to offer, of course!

However, as they have similar properties and effects, people often ask, “What is the difference between Wegony and Ozempic?” Or “Which one is more effective and suitable to use?”

While the FDA approved Ozempic for individuals with diabetes in 2017, it also clarified that Wegovy is good for people who want to handle overweight and other health issues in 2021.

Scroll down to learn more in-depth details about Wegony vs Ozempic!

Comparing Wegovy vs. Ozempic – Key Differences

Without a doubt, both these medicines serve their purpose nicely, and patients seem to be very happy with the results they give. So today, we’ll take a look at the major differences between these drugs, including dosage, insurance coverage, usage, side effects, and more. 

No more talk; let’s have a look!

1) About Ozempic & Wegovy

Ozempic is one of the most popular drugs for weight loss in the U.S. Not only this but it is also intended to assist people in handling type 2 diabetes well.

As per the FDA, it has been shown to reduce stroke and heart attack risks, as well as lower blood sugar levels. Individuals with obesity use this injectable semaglutide once a week.

As far as Wegovy is concerned, it is approved by the FDA for weight loss in both children and adults (12 and older). It is undeniably intended to work with a healthy diet and regular physical activity.

If you have excess weight, you should take this injection once a week for maximum results.

2) Dosage and Administration Routes

Well, Ozempic is generally initiated at a lower maintenance dose for blood glucose control. You can further escalate it depending on your health situation and medical conditions (if any).

On the contrary, approved Wegovy also possesses the same ingredient, but it is prescribed at comparatively higher doses for chronic weight management or losing more weight. 

There’s no doubt that both of them are administrated using injection pens through subcutaneous injections. Yes, you read that right! 

However, remember that the dosage schedule and administration may differ depending on your treatment plan for diabetes or obesity.

3) Accessibility & Ease of Use

Both Ozempic and Wegovy  are equipped with multi-dose pens (injectable) that are designed for ease of use and administration.

Anyhow, remember that the need for a very long-term dose can impact patients’ adherence in particular.

The accessibility point might hinge on the recommendation of the healthcare provider and the insurance coverage.

It can be influenced by factors such as the individual’s cardiovascular health conditions or obesity management needs.

4) Use Cases of Both Medications

Though Ozempic and Wegovy have the same ingredient, as we mentioned earlier, the use of FDA approved Wegovy is more on the body weight loss journey as well as prevention for different heart diseases.

Ozempic, in addition, is dedicated to helping adults with type 2 diabetes. Clear enough?

The Food and Drug Administration has approved these body weight loss medications for the following uses:

Wegovy is supposed to help:

  • People with a BMI of around 27 or higher and a minimum of one weight-related condition, like type 2 diabetes, high cholesterol, or high blood pressure
  • With long-term weight management and weight loss, along with physical activity and diet, in people with a body mass index of 30 or even higher
  • A toddler of 12 years or above with a BMI in almost the 95th percentile or higher

Ozempic is supposed to assist with the following:

  • Lowering the serious cardiovascular risks and blood vessel issues in people with diabetes
  • Managing blood sugar levels in individuals with diabetes

Healthcare providers sometimes prescribe Ozempic (off-label) to assist with long-term weight loss management. With off-label usage, doctors suggest a drug for use that is not FDA-approved for weight loss.

5) Eligibility Criteria

People with obesity who meet particular BMI criteria can be eligible for Wegovy. It includes adults with a body mass index of 30 or more. 

You can even qualify if you’ve around 27 BMI and another weight-relation condition. Examples of such conditions may be high cholesterol, type 2 diabetes, and high blood pressure.

What’s more, this medicine is approved by the FDA for chronic weight management. To be eligible, you should have a BMI at or more than 95% for sex and age.

Many patients with type 2 diabetes are mostly prescribed Ozempic as it assists in lowering blood glucose levels. 

When you have been prescribed this drug and do not have diabetes, it is considered particular off label use. Ozempic is not actually approved for use in individuals who are under 18.

6) Dosage

When you begin taking Ozempic or Wegovy initially, it’s important to stick to a low dose. Every four weeks, your physician will increase the dosage himself until you reach the specific target amount. However, how you actually inject the medicine will vary depending on the medication.

Normally, the schedule for Wegovy dosage is as follows:

  • 1st month: 0.25 mg once in a week (on first treatment)
  • 2nd month: 0.5 mg once in a week
  • 3rd month: 1 mg once in a week
  • 4th month:1.7 mg once in a week
  • 5th month: 2.4 mg once in a week

If you are not able to bear the suggested target dosage of Wegovy, your healthcare provider will have to take you to around 1.7 mg once a week instead.

Additionally, the FDA recommends the dosage schedule of Ozempic as follows:

  • 1st month: 0.25 mg once in a week (on first treatment)
  • 2nd month: 0.5 mg once in a week

If required, your dosage might be increased to 2 mg a week.

7) Overall Cost

The overall cost of both Wegovy and Ozempic varies depending on the specific treatment plan your healthcare provider suggests and your pharmacy and insurance plan.

You can visit their official website to find out if there are any discounts. Plus, there are many other ways to save on costs, like Patient Assistant Programs, Coupons, Insurance, and more.

Both Ozempic and Wegovy are particularly brand-name drugs, and they aren’t available in generic form at the present time.

8) Insurance Coverage 

The coverage for insurance is different for both these drugs — depending on your current insurance plan. For instance, your plan might not cover Wegovy for weight loss.

Even so, treating type 2 diabetes may give you some great coverage and perks. So, it’s best to examine your plan by clinical trials for any particular coverage details.

If you currently have commercial insurance, you will be able to save on this prescription with a manufacturer’s savings card. That means you can pay just $0 for Wegovy and only $25 for Ozempic in some scenarios.

Other than that, patient assistance programs are also available for Ozempic and Wegovy if you are eligible.

9) Potential Side Effects

Like the endless benefits both these weight loss medications have to offer, they also come up with a few drawbacks that every patient with obesity must be aware of.

Some of the most common negative sides of Ozemic involve:

  • Diarrhea
  • Stomach pain
  • Vomiting
  • Nausea
  • Constipation 
  • Abdominal pain

In some cases, it may also cause thyroid C-cell tumours (as a boxed warning). 

Doctors must consider the health situation of people with obesity, such as their history of pancreatic disease, bariatric surgery, thyroid cancer, heart attacks, established cardiovascular disease, medullary thyroid cancer, or other major adverse cardiovascular events while prescribing it.

The common drawbacks of Wegovy are:

  • Tiredness
  • Vomiting
  • Diarrhea
  • Nausea
  • Constipation
  • Dizziness
  • Upset stomach 
  • Headache
  • Fas
  • Belching
  • Feeling bloated
  • Sore throat
  • Runny nose
  • Heartburn
  • Stomach flu
  • Allergic reactions
  • Bladder-related issues

This one drug isn’t suggested for those patients who have obesity and a family or personal history of Multiple Endocrine Neoplasia syndrome or medullary thyroid carcinoma.

Bottom Line – Wegovy vs Ozempic

Ozempic and Wegovy have several similarities. Both are used once a week and contain active semaglutide. However, they do have a few key differences, like dosage, approved uses, and effectiveness.

In this article, we’ve mentioned their notable differences and which is more effective.

Furthermore, you can talk to your healthcare provider to make a final informed decision according to your health conditions, like certain cancers, cardiovascular risk, fatty liver, heart disease, established cardiovascular disease, or another chronic disease to lessen adverse effects.

So, which one do you think would better suit your needs? Let us know in the comment section!